This indicator shows the HIV incidence rate in cases per 100,000 population.

The Centers for Disease Control and Prevention estimates that approximately one million Americans were living with HIV as of 2006 and estimates that one in five people infected with HIV do not know they are infected. Men who have sex with men of all races, African Americans, and Hispanics/Latinos are disproportionately affected by HIV. More HIV infections occur among young people under age 30 than any other age group.

The total number of people living with HIV in the U.S. is increasing because fewer people die of complications from HIV each year. Improvements in treatment and improved access to treatment allow people with HIV to live longer and healthier lives. The annual number of new HIV infections has remained relatively stable in the U.S. in recent years; however, more than 55,000 new cases are reported annually and HIV/AIDS remains a significant cause of illness, disability, and death in the U.S.